Endocrine Abstracts

The HPA axis facilitates adaptation to stress and is essential for metabolism and health, but dysregulation of the HPA axis compromises resilience and promotes vulnerability to stress-related diseases. This includes diseases of the brain where an aberrant stress hormone action targeting susceptibility pathways causes emotional and cognitive disturbances, and affects the onset and progression of neurodegenerative processes, while impairing recovery and neurogenesis. This action...